Health Advisor

If there's anything the Ozempic craze has taught us, it's that people are hungry for weight loss solutions. But as the world leans into wellness, many are now looking beyond pharmaceuticals, turning their gaze to nature's arsenal for blood sugar balance and metabolic health. The  2023 report  from the World Obesity Federation estimates that the economic impact of overweight and obesity will surpass $4.3 trillion annually by 2035. In the U.S., the  CDC  reports the prevalence of obesity in adults was 41.9% measured from 2017 to March 2020. This represented an increase from 30.5% from 1999 to 2000. The estimated annual medical costs were roughly $173 billion in 2019 dollars. Prescriptions for semaglutide have doubled since mid-2021, rising to more than 1.2 million. In April 2023, a spokesperson for Novo Nordisk, maker of semaglutide, said the drugs are now available in pharmacies nationwide. Semaglutide is sold under the name Ozempic as a diabetes drug and under the na...

What’s NMN? NMN stands for Nicotinamide MonoNucleotide, a molecule naturally occurring in all life forms. At the molecular level, it is a ribo-nucleotide, which is a basic structural unit of the nucleic acid RNA. Structurally, the molecule is composed of a nicotinamide group, a ribose and a phosphate group (Figure 1). NMN is the direct precursor of the essential molecule nicotinamide adenine dinucleotide (NAD+) and is considered a key component to increase NAD+ levels in cells.   What is Nicotinamide Adenine Dinucleotide (NAD+)? NAD+ is an essential coenzyme required for life and cellular functions. Enzymes are catalysts that make biochemical reactions possible. Coenzymes are  ‘helper’ molecules that enzymes need in order to function.  What Does NAD+ Do? NAD+ is the most abundant molecule in the body besides water, and without it, an organism would die. NAD+ is used by many proteins throughout the body, such as the sirtuins, which r...

David Sinclair, Ph.D., A.O. is a Professor in the Department of Genetics and co-Director of the Paul F. Glenn Center for Biology of Aging Research at Harvard Medical School . Dr. David Sinclair’s main research interest is the epigenetics of aging, with a focus on epigenetic reprogramming of aging (e.g. via Yamanaka factors ), NAD+ metabolism and sirtuins, and NAD+ precursors like NR and NMN . You may have come across his published, New York Times best-selling book on aging, “ Lifespan: Why We Age – And Why We Don’t Have To ”, going deeper into those subjects. So what supplements does Professor David Sinclair take to live longer? Keep in mind that to date, Dr. David Sinclair has made a point to not promote or endorse any supplement products. We compiled this list from interviews and books in which Professor David Sinclair mentions supplements he takes. We don’t know if he still takes these supplements, or whether he takes additional supplements ...